Following
last season when the agents were in an artificial framework and encountered the Ghost Rider, they escaped and
taken to a Kree station called the Lighthouse where they encounter an alien species called the
Vrellnexians as well as the Kree race. The agents discover they have traveled through time when Earth is destroyed. After the destruction of Earth, the Kree stepped in and removed humanity's history so they can focus on the future. The Vrellnexians now inhabit Earth hunting down the last of the humans. We discover the destruction of Earth was caused by Quake. Sanara a Kree guard works for Kasius who runs the Lighthouse. Fitz arrives in the future to help his teammates. He discovers they were taken into the future by a prophecy to the year 2091. Fitz sleeps and awakens in the future where he rescues Simmons and Quake. They rescue the rest of the team and head to Earth.
Mack and Elena leads the human rebellion against Kasius while Coulson and the team return to the Lighthouse. The Agents return back to their own time only to be hunted down led by General Hale and her daughter who has cut off the arms of Yo-Yo. Now General Hale is building a team which includes the Absorbing Man to capture the Coulson and his team. Quake's powers are restored to deal with the Gravitonium to seal the rift as General Hale secretly works with Hydra.
General Hale takes Coulson and convinces him she needs Quake which Coulson refuses. The Absorbing Man rescues Coulson and Talbot from Hale and escape while the Absorbing Man is stopped. However Hale still has mental controls over Talbot who is later freed by Coulson. Hale's daughter is killed by Yo Yo after she absorbs part of the Gravitonium. Now Hale wants revenge and sends Hydra after Shield.
The Qovos launches an attack on the Lighthouse to acquire the Gravitonium as Glenn Talbot submits himself to the it so he can stop them. Talbot has become Graviton the Destroyer of Worlds. Now Quake uses her powers to send Graviton into space. Fitz dies however his younger self was sent into the future so its up to the agents to find him. Agent Coulson is left on an island to pass away peacefully with May joining him.
